Coolgut Chewable Tablet 150 mcg
Coolgut Chewable Tablet 150 mcg Uses, Dosage, Side Effects, Food Interaction and all others data.
Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.
| Trade Name | Coolgut Chewable Tablet 150 mcg |
| Generic | Hyoscine Hydrobromide |
| Weight | 150 mcg |
| Type | Chewable Tablet |
| Therapeutic Class | Anti-emetic drugs |
| Manufacturer | Incepta Pharmaceuticals Ltd. |
| Available Country | Bangladesh |
| Last Updated: | October 19, 2023 at 6:27 am |
Uses
Motion sickness
Dosage
Coolgut Chewable Tablet 150 mcg dosage
Adult & Children over 12 years: 300 mcg 30 mins before journey, then 300 mcg 6 hrly if needed. Max: 3 doses in 24 hr.
Children 4-12 years: 1 tablet (150 mcg) 30 mins before journey. Maximum 2 tablet in 24 hours.
Children 3-4 years: ½ tab 30 mins before journey. Maximum 1 tablet in 24 hours.
Side Effects
Flushing, postural hypotension, tachycardia, fibrillation. Rarely psychotic reactions. Dizziness, drowsiness, fatigue, headache, memory loss. Dry skin, erythema, increased sensitivity to light, rash. Bloatedness, constipation, dry throat, dysphagia, nausea, vomiting, xerostomia. Dysuria, urinary retention. Tremor, weakness. Impaired accommodation, blurred vision, cycloplegia, dryness, narrow-angle glaucoma, increased intraocular pain, itching, photophobia, pupil dilation. Dry nose. Decreased diaphoresis, heat intolerance. Ophthalmic: Somnolence, dermatitis, oedema, exudate, follicular conjunctivitis, increased IOR local irritation, photophobia, vascular and respiratory congestion.
Precaution
Hepatic/renal disease, pyloric stenosis, urinary retention, prostatic hyperplasia, psychosis, seizure disorders, ulcerative colitis, coronary artery disease, tachyarrhythmias, heart failure, hypertension. Elderly, children, pregnancy, lactation
Interaction
Additive sedative effects with alcohol or other CNS depressants. Reduced effects with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine, tacrine).
Pregnancy & Breastfeeding use
Pregnancy Category C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Contraindication
Narrow-angle glaucoma, acute haemorrhage, paralytic ileus, tachycardia due to cardiac insufficiency, myasthenia gravis.
Innovators Monograph
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