Cortisona
Cortisona Uses, Dosage, Side Effects, Food Interaction and all others data.
A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisona itself is inactive. It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
Trade Name | Cortisona |
Availability | Prescription only |
Generic | Cortisone |
Cortisone Other Names | Cortisona, Cortisone, Cortisonum, Kendall's compound E, Kortison, Reichstein's substance Fa |
Related Drugs | Humira, Cosentyx, Promacta, aspirin, prednisone, ibuprofen, meloxicam, naproxen, diclofenac ophthalmic, Cymbalta |
Type | |
Formula | C21H28O5 |
Weight | Average: 360.444 Monoisotopic: 360.193674006 |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Cortisona Cholesterol interaction
[Moderate] Corticosteroids may elevate serum triglyceride and LDL cholesterol levels if used for longer than brief periods.
Patients with preexisting hyperlipidemia may require closer monitoring during prolonged corticosteroid therapy, and adjustments made accordingly in their lipid-lowering regimen.
Cortisona Hypertension interaction
[Moderate] Corticosteroids may cause hypernatremia, hypokalemia, fluid retention, and elevation in blood pressure.
These mineralocorticoid effects are most significant with fludrocortisone, followed by hydrocortisone and cortisone, then by prednisone and prednisolone.
The remaining corticosteroids, betamethasone, dexamethasone, methylprednisolone, and triamcinolone, have little mineralocorticoid activities.
However, large doses of any corticosteroid can demonstrate these effects, particularly if given for longer than brief periods.
Therapy with corticosteroids should be administered cautiously in patients with preexisting fluid retention, hypertension, congestive heart failure, and Dietary sodium restriction and potassium supplementation may be advisable.
Cortisona Drug Interaction
Unknown: diphenhydramine, diphenhydramine, atorvastatin, atorvastatin, pregabalin, pregabalin, levothyroxine, levothyroxine, acetaminophen, acetaminophen, cyanocobalamin, cyanocobalamin, ascorbic acid, ascorbic acid, cholecalciferol, cholecalciferol, alprazolam, alprazolam, cetirizine, cetirizine
Cortisona Disease Interaction
Major: GI perforation, infections, PUD, vaccinationModerate: (+) tuberculin test, cirrhosis, depression/psychoses, diabetes, electrolyte imbalance, fluid retention, hyperadrenocorticalism, hyperlipidemia, hypothyroidism, liver disease, MI, myasthenia gravis, myopathy, ocular herpes simplex, ocular toxicities, osteoporosis, scleroderma, strongyloidiasis, thromboembolism
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