Cyclacillin
Cyclacillin Uses, Dosage, Side Effects, Food Interaction and all others data.
A cyclohexylamido analog of penicillanic acid.
Cyclacillin, a penicillin, is a cyclohexylamido analog of penicillanic acid. Cyclacillin is more resistant to beta-lactamase hydrolysis than ampicillin, is much better absorbed when given by mouth and, as a result, the levels reached in the blood and in the urine are considerably higher than those obtained with the same dose of ampicillin. Cyclacillin has been replaced by newer penicillin treatments.
Trade Name | Cyclacillin |
Generic | Cyclacillin |
Cyclacillin Other Names | Ciclacilina, Ciclacillin, Ciclacilline, Ciclacillinum, Cyclacillin |
Type | |
Formula | C15H23N3O4S |
Weight | Average: 341.426 Monoisotopic: 341.140926929 |
Groups | Approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of bacterial infections caused by susceptible organisms.
How Cyclacillin works
The bactericidal activity of cyclacillin results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Cyclacillin is stable in the presence of a variety of b-lactamases, including penicillinases and some cephalosporinases.
Toxicity
Symptoms of overdose include severe diarrhea, nausea and vomiting.
Elimination Route
Moderately absorbed.
Innovators Monograph
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