Cyclaine
Cyclaine Uses, Dosage, Side Effects, Food Interaction and all others data.
Cyclaine hydrochloride is also known as cyclaine and osmocaine. It is a short acting local anesthetic that acts through inhibition of sodium channels. Patients experience an overdose may present with headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function. Cyclaine has been discontinued in the US market.
Cyclaine is a local ester-class anesthetic. Local anesthetics produce a transient block of nerve conduction by interfering with sodium channels. This effect of the anesthetic interferes with the development of an action potential across the nerve.
| Trade Name | Cyclaine |
| Generic | Hexylcaine |
| Hexylcaine Other Names | Hexilcaina, Hexylcaine, Hexylcainum |
| Type | |
| Formula | C16H23NO2 |
| Weight | Average: 261.3593 Monoisotopic: 261.172878985 |
| Groups | Approved, Withdrawn |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Used as a local anesthetic for surface application, infiltration or nerve block
How Cyclaine works
Hexyl caine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is thus inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel.
Toxicity
Symptoms of anesthetic overdose include headache, tinnitus, circumoral and tongue paresthesias, restlessness, talkativeness, facial twitching, convulsions, respiratory arrest, and cardiac depression
Half Life
<10 minutes
Innovators Monograph
You find simplified version here Cyclaine
