Cyclandelate

Cyclandelate Uses, Dosage, Side Effects, Food Interaction and all others data.

A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia. Cyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries.

Cyclandelate is in a class of drugs called vasodilators. Cyclandelate relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.

Trade Name Cyclandelate
Availability Discontinued
Generic Cyclandelate
Cyclandelate Other Names Ciclandelato, Cyclandelate, Cyclandelatum
Related Drugs amlodipine, nitroglycerin, nifedipine, Norvasc, prazosin, doxazosin, vitamin e, Alpha E, E-400 Clear
Type Oral
Formula C17H24O3
Weight Average: 276.3707
Monoisotopic: 276.172544634
Groups Approved
Therapeutic Class
Manufacturer
Available Country United States
Last Updated: September 19, 2023 at 7:00 am
Cyclandelate
Cyclandelate

Uses

Cyclandelate is a vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis.

Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.

How Cyclandelate works

Cyclandelate produces peripheral vasodilation by a direct effect on vascular smooth muscle. Pharmacological action may be due to calcium-channel antagonism.

Toxicity

Acute oral toxicity (LD50): 3950 mg/kg [Guinea pig]

Food Interaction

  • Take with food. Food reduces irritation.

Elimination Route

Well absorbed following oral administration.

Innovators Monograph

You find simplified version here Cyclandelate

*** Taking medicines without doctor's advice can cause long-term problems.
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