Cyclapen-W
Cyclapen-W Uses, Dosage, Side Effects, Food Interaction and all others data.
A cyclohexylamido analog of penicillanic acid.
Cyclapen-W, a penicillin, is a cyclohexylamido analog of penicillanic acid. Cyclapen-W is more resistant to beta-lactamase hydrolysis than ampicillin, is much better absorbed when given by mouth and, as a result, the levels reached in the blood and in the urine are considerably higher than those obtained with the same dose of ampicillin. Cyclapen-W has been replaced by newer penicillin treatments.
Trade Name | Cyclapen-W |
Generic | Cyclacillin |
Cyclacillin Other Names | Ciclacilina, Ciclacillin, Ciclacilline, Ciclacillinum, Cyclacillin |
Type | |
Formula | C15H23N3O4S |
Weight | Average: 341.426 Monoisotopic: 341.140926929 |
Groups | Approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of bacterial infections caused by susceptible organisms.
How Cyclapen-W works
The bactericidal activity of cyclacillin results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Cyclapen-W is stable in the presence of a variety of b-lactamases, including penicillinases and some cephalosporinases.
Toxicity
Symptoms of overdose include severe diarrhea, nausea and vomiting.
Elimination Route
Moderately absorbed.
Innovators Monograph
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