Dalfopristina
Dalfopristina Uses, Dosage, Side Effects, Food Interaction and all others data.
Dalfopristina is a combination of two antibiotics (Dalfopristina and quinupristin) used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium. It is not effective against Enterococcus faecalis infections. Dalfopristina inhibits the early phase of protein synthesis in the bacterial ribosome and quinupristin inhibits the late phase of protein synthesis.
Dalfopristina is a streptogramin antibiotic, derived from pristinamycin IIA.
| Trade Name | Dalfopristina |
| Generic | Dalfopristin |
| Dalfopristin Other Names | Dalfopristin, Dalfopristina, Dalfopristine, Dalfopristinum |
| Type | |
| Formula | C34H50N4O9S |
| Weight | Average: 690.85 Monoisotopic: 690.32985038 |
| Protein binding | Moderate |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Dalfopristina is an antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes.
For the treatment of bacterial infections (usually in combination with quinupristin).
Dalfopristina is also used to associated treatment for these conditions: Bacterial Infections, Infections caused by penicillinase-producing staphylococci, Complicated Skin and subcutaneous tissue bacterial infection
How Dalfopristina works
The site of action of dalfopristin is the bacterial ribosome. Dalfopristina has been shown to inhibit the early phase of protein synthesis.
Food Interaction
No interactions found.Half Life
The elimination half-life is approximately 0.70 hours.
Innovators Monograph
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