Davedax
Davedax Uses, Dosage, Side Effects, Food Interaction and all others data.
Davedax is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sold under tradenames including Edronax, Norebox, Prolift, Solvex, Davedax or Vestra. Davedax has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.
Davedax is a selective noradrenaline reuptake inhibitor (NaRI), the first drug of new antidepressant class. Davedax is an a-ariloxybenzyl derivative of morpholine. Davedax is primarily used to treat depression but has also been found useful in the treatment of narcolepsy and panic disorders.
| Trade Name | Davedax |
| Generic | Reboxetine |
| Reboxetine Other Names | Reboxetina, Reboxetine |
| Type | |
| Formula | C19H23NO3 |
| Weight | Average: 313.397 Monoisotopic: 313.167793605 |
| Protein binding | 98% |
| Groups | Approved, Experimental |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Davedax is a drug used for the acute treatment of major depression and for maintenance therapy of depression.
For the treatment of clinical depression.
Davedax is also used to associated treatment for these conditions: Major Depressive Disorder (MDD), Maintenance
How Davedax works
Davedax is a selective inhibitor of noradrenaline reuptake. It inhibits noradrenaline reuptake in vitro to a similar extent to the tricyclic antidepressant desmethylimipramine. Davedax does not affect dopamine or serotonin reuptake and it has low in vivo and in vitro affinity for adrenergic, cholinergic, histaminergic, dopaminergic and serotonergic receptors.
Toxicity
Reports of seizures (rare) have been reported
Elimination Route
Davedax is rapidly and extensively absorbed following oral administration.
Half Life
12.5 hours
Innovators Monograph
You find simplified version here Davedax
