Desmethylmethadone
Desmethylmethadone Uses, Dosage, Side Effects, Food Interaction and all others data.
Desmethylmethadone is used as an opioid antitussive in combination with Oxilofrine. It is marketed in Canada by Valeant under the tradename Cophylac.
Desmethylmethadone is an opioid which suppresses coughing by central and peripheral mechanisms .
| Trade Name | Desmethylmethadone |
| Generic | Normethadone |
| Normethadone Other Names | Desmethylmethadone, Isomethadone I, Normethadone |
| Type | |
| Formula | C20H25NO |
| Weight | Average: 295.426 Monoisotopic: 295.193614429 |
| Groups | Approved, Illicit |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Desmethylmethadone is an opioid antitussive used to treat a cough associated with inflamed mucosa.
For use in the treatment of cough when other less potent treatments have failed .
How Desmethylmethadone works
Desmethylmethadone activates central opioid receptors in the medulla to supress the cough reflex . It also likely activates peripheral opioid receptors to inhibit signalling by irritant receptors of the airway.
Toxicity
The toxic effects of normethadone are similar to those of other opioids. It can produce respiratory depression, depression of central nervous system function, and constipation .
Food Interaction
- Avoid alcohol. Ingesting alcohol may cause additive CNS depressive effects.
Innovators Monograph
You find simplified version here Desmethylmethadone
