Dimethylchondrocurarine Uses, Dosage, Side Effects and more
Dimethyltubocurarinium (INN) or metocurine (USAN), also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant. Patients on chronic anticonvulsant drugs are relatively resistant to metocurine.
| Attribute | Details |
|---|---|
| Trade Name | Dimethylchondrocurarine |
| Availability | Discontinued |
| Generic | Metocurine |
| Metocurine Other Names | Dimethylchondrocurarine |
| Type | |
| Formula | C40H48N2O6 |
| Weight | Average: 652.8189 Monoisotopic: 652.351237278 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Dimethylchondrocurarine is a muscle relaxant.
How Dimethylchondrocurarine works
Dimethylchondrocurarine antagonizes the neurotransmitter action of acetylcholine by binding competitively with cholinergic receptor sites on the motor end-plate. This antagonism is inhibited, and neuromuscular block reversed, by acetylcholinesterase inhibitors such as neostigmine, edrophonium, and pyridostigmine.
Drug Interaction
Moderate: fentanyl, fentanylUnknown: sulfamethoxazole / trimethoprim, sulfamethoxazole / trimethoprim, levothyroxine, levothyroxine
Disease Interaction
Major: electrolyte imbalance, histamine release, liver disease, myasthenia gravis, paresis, pulmonary impairModerate: renal dysfunction
