Disodium glycerol phosphate Uses, Dosage, Side Effects and more
Disodium glycerol phosphate is one of several glycerophosphate salts. It is used clinically to treat or prevent low phosphate levels . Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body . The extent of this reaction is dependent on the activity of serum alkaline phosphatases.
Glycerophosphate acts as a source of inorganic phosphate through hydrolysis .
Trade Name | Disodium glycerol phosphate |
Generic | Sodium glycerophosphate |
Sodium glycerophosphate Other Names | Disodium glycerol phosphate |
Type | |
Formula | C3H7Na2O6P |
Weight | Average: 216.036 Monoisotopic: 215.9775635 |
Groups | Approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | January 7, 2025 at 1:49 am |
Uses
Disodium glycerol phosphate is a medication used to treat hypophosphatemia.
Disodium glycerol phosphate is indicated for use as a source of phosphate in total parenteral nutrition . It is used in combination with amino acids, dextrose, lipid emulsions, and other electrolytes.
Disodium glycerol phosphate is also used to associated treatment for these conditions: Total parenteral nutrition therapy
How Disodium glycerol phosphate works
Disodium glycerol phosphate acts as a donor of inorganic phosphate . See Monopotassium phosphate for a description of phosphate's role in the body.
Food Interaction
No interactions found.Elimination Route
Peak serum phosphate concentration is reached in 4h .
Half Life
Inorganic phosphate has a half-life of elimination of 2.06h .
Elimination Route
Inorganic phosphate produced is eliminated in the urine . There may be a very small amount of glycerophosphate excreted in the urine unchanged.