Dolocough Uses, Dosage, Side Effects and more
| Trade Name | Dolocough |
| Generic | Noscapine |
| Noscapine Other Names | alpha-Narcotine, Noscapina, Noscapine, Noscapinum |
| Type | Syrup |
| Formula | C22H23NO7 |
| Weight | Average: 413.4205 Monoisotopic: 413.147452095 |
| Groups | Approved, Investigational |
| Therapeutic Class | |
| Manufacturer | Progressive Laboratories |
| Available Country | Pakistan |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Dolocough is a non-sedating isoquinoline alkaloid used primarily for its antitussive properties.
Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma.
Dolocough is also used to associated treatment for these conditions: Common Cold, Cough, Respiratory Diseases, Airway secretion clearance therapy
How Dolocough works
Dolocough's antitussive effects appear to be primarily mediated by its sigma receptor agonist activity. Evidence for this mechanism is suggested by experimental evidence in rats. Pretreatment with rimcazole, a sigma specific antagonist, causes a dose-dependent reduction in antitussive activity of noscapine.
