Dukoral

Dukoral Uses, Dosage, Side Effects, Food Interaction and all others data.

Cholera vaccine is available as oral preparations containing either live attenuated or inactivated strains. Oral cholera vaccines appear to be more effective than parenteral vaccines. It may be used in adults and children aged ≥2 yr who are travelling to areas of risk.

Dukoral
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Dukoral
Generic	Oral Cholera Vaccine
Weight	3ml,
Type	Oral Suspension
Therapeutic Class	Vaccines, Anti-sera & Immunoglobulin
Manufacturer	Healthcare Pharmacuticals Ltd
Available Country	Bangladesh, Canada, United States, Switzerland
Last Updated:	September 19, 2023 at 7:00 am

Uses

Active immunisation against cholera

Dosage

Dukoral dosage

Adult: For primary vaccination schedule: Given as a suspension (in doses of 3 ml, mixed with sodium hydrogen carbonate solution): 2 doses, at wkly intervals. Complete immunisation 1 wk prior to potential exposure. If >6 wk have elapsed between doses, primary immunisation course should be re-initiated. A single booster dose may be given after 2 yr to maintain protection.

Child: For primary vaccination schedule: Given as a suspension (in doses of 3 ml, mixed with sodium hydrogen carbonate solution): 2-6 yr: 3 doses, at wkly intervals; >6 yr: 2 doses, at wkly intervals. Complete immunisation 1 wk prior to potential exposure. If >6 wk have elapsed between doses, primary immunisation course should be re-initiated. A single booster dose may be given after 6 mth (2-6 yr) or 2 yr (>6 yr), depending on the age of the patient to maintain protection.

Should be taken on an empty stomach. Take on an empty stomach. Avoid food & drink 1 hr before & 1 hr after vaccination.

Side Effects

GI disturbances, headache, dizziness and respiratory symptoms. Fever and malaise, hypersensitivity reactions and neurological symptoms.

Precaution

Immunisation should be delayed in patients suffering from acute febrile illness or acute GI illness. Not recommended for use in children <2 yr. Limited data on efficacy and safety of the vaccine usage in HIV-infected patients. Additional protective measures should be undertaken as the vaccine does not provide complete protection against cholera infection.

Interaction

Not to be used within 3 wk of immunoglobulin admin. Reduced response may occur in patients who are concurrently receiving immunosuppressant treatment e.g. antineoplastics, corticosteroids at therapeutic doses. Oral, encapsulated typhoid vaccine should not be admin within 8 hr of cholera vaccine admin.