Emeromin
Emeromin Uses, Dosage, Side Effects, Food Interaction and all others data.
Emeromin is an antihistamine used in eye drops to treat allergic conjunctivitis.
Emeromin is a relatively selective H1-receptor antagonist.
| Trade Name | Emeromin |
| Generic | Emedastine |
| Emedastine Other Names | Emedastina, Emedastine, Emedastinum |
| Type | |
| Formula | C17H26N4O |
| Weight | Average: 302.4145 Monoisotopic: 302.210661474 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | Japan |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Emeromin is a selective H1-receptor antagonist used topically to manage symptoms of allergic conjunctivitis.
For the temporary relief of the signs and symptoms of allergic conjunctivitis.
Emeromin is also used to associated treatment for these conditions: Seasonal Allergic Conjunctivitis
How Emeromin works
Emeromin is a relatively selective, histamine H1 antagonist. In vitro examinations of emedastine's affinity for histamine receptors demonstrate relative selectivity for the H1 histamine receptor. In vivo studies have shown concentration-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva following topical ocular administration. Emeromin appears exert negligible effects on adrenergic, dopaminergic and serotonin receptors.
Toxicity
Somnolence and malaise have been reported following daily oral administration.
Food Interaction
No interactions found.Elimination Route
Ophthalmic use of emedastine usually does not produce measurable plasma concentrations.
Half Life
The elimination half-life in the plasma is 3-4 hours following oral administration.
Elimination Route
Following oral administration, approximately 44% of the total dose can be recovered in the urine over the 24-hour period, with only 3.6% of the dose excreted as unchanged form. Two primary metabolites, 5- and 6-hydroxyemedastine, are excreted in the urine as both free and conjugated forms.
Innovators Monograph
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