ENMD-1198 Uses, Dosage, Side Effects and more

Trade Name ENMD-1198
Generic ENMD-1198
Type
Formula C20H25NO2
Weight Average: 311.425
Monoisotopic: 311.188529049
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: January 7, 2025 at 1:49 am

Uses

Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.

How ENMD-1198 works

ENMD-1198, a new chemical entity (NCE) based on a modified chemical structure of 2-methoxyestradiol (2ME2), is designed to decrease metabolism while retaining 2ME2's multiple mechanisms of action, including inducing apoptosis, disrupting microtubules, and inhibiting HIF-1 alpha. In preclinical studies, ENMD-1198 has been shown to be an orally active, antimitotic agent that leads to arrest of cell division and apoptosis in tumor cells. It also exerts antiangiogenic activity that further contributes to its overall antitumor effects.

Innovators Monograph

*** Taking medicines without doctor's advice can cause long-term problems.
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