RAF-265 Uses, Dosage, Side Effects and more
| Trade Name | RAF-265 |
| Generic | RAF-265 |
| Type | |
| Formula | C24H16F6N6O |
| Weight | Average: 518.423 Monoisotopic: 518.128978137 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in melanoma.
How RAF-265 works
CHIR-265 binds and inhibits Raf kinases, which may result in a reduction of tumor cell growth and proliferation, and tumor cell death. In addition, this agent inhibits vascular endothelial growth factor receptor type 2 (VEGFR-2), thereby disrupting tumor angiogenesis. Raf kinases are critical enzymes in the Ras/Raf/MEK/ERK signaling pathway and are frequently upregulated in neoplasms.
