RAF-265

RAF-265 Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name RAF-265
Generic RAF-265
Type
Formula C24H16F6N6O
Weight Average: 518.423
Monoisotopic: 518.128978137
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
RAF-265
RAF-265

Uses

Investigated for use/treatment in melanoma.

How RAF-265 works

CHIR-265 binds and inhibits Raf kinases, which may result in a reduction of tumor cell growth and proliferation, and tumor cell death. In addition, this agent inhibits vascular endothelial growth factor receptor type 2 (VEGFR-2), thereby disrupting tumor angiogenesis. Raf kinases are critical enzymes in the Ras/Raf/MEK/ERK signaling pathway and are frequently upregulated in neoplasms.

Innovators Monograph

You find simplified version here RAF-265

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