RAF-265
RAF-265 Uses, Dosage, Side Effects, Food Interaction and all others data.
Trade Name | RAF-265 |
Generic | RAF-265 |
Type | |
Formula | C24H16F6N6O |
Weight | Average: 518.423 Monoisotopic: 518.128978137 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in melanoma.
How RAF-265 works
CHIR-265 binds and inhibits Raf kinases, which may result in a reduction of tumor cell growth and proliferation, and tumor cell death. In addition, this agent inhibits vascular endothelial growth factor receptor type 2 (VEGFR-2), thereby disrupting tumor angiogenesis. Raf kinases are critical enzymes in the Ras/Raf/MEK/ERK signaling pathway and are frequently upregulated in neoplasms.
Innovators Monograph
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