Enoximona

Enoximona Uses, Dosage, Side Effects, Food Interaction and all others data.

Enoximona is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. It is used in patients with congestive heart failure. Trials were halted in the U.S., but the drug is used in various countries.

Enoximona is a phosphodiesterase inhibitor (type III) that increases the force of contraction of the heart and dilates blood vessels. In June 2005, Myogen announced that they were discontinuing development of enoximone due to negative results. The drug is approved for use in the UK.

Enoximona
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Enoximona
Generic	Enoximone
Enoximone Other Names	Enoximona, Enoximone, Enoximonum
Type
Formula	C₁₂H₁₂N₂O₂S
Weight	Average: 248.301 Monoisotopic: 248.061948328
Protein binding	85%
Groups	Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Enoximona is a selective phosphodiesterase inhibitor indicated in the short term treatment of congestive heart failure.

For the treatment of congestive heart failure.

Enoximona is also used to associated treatment for these conditions: Congestive Heart Failure (CHF)

How Enoximona works

Further research is required to determine accurately the mechanism of action of drugs with phosphodiesterase inhibitory activity, however, inhibition of PDE3 inhibits degredation of cGMP. This allows for increased NO release and vascular relaxation.