Fimanta

Fimanta Uses, Dosage, Side Effects, Food Interaction and all others data.

Fimanta is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimanta was initially approved September 9th, 2010 in South Korea and is marketed under the brand name Kanarb by Boryung Pharmaceuticals.

Fimanta is a selective angiotensin receptor 1 (AR1) inhibitor . It acts to lower blood pressure by inhibiting vasoconstriction

Trade Name Fimanta
Generic Fimasartan
Fimasartan Other Names Fimasartan
Weight 60mg, 120mg
Type Tablet
Formula C27H31N7OS
Weight Average: 501.65
Monoisotopic: 501.23107982
Groups Investigational
Therapeutic Class
Manufacturer Ajanta Pharma Ltd
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Fimanta
Fimanta

Uses

Fimanta is an angiotensin II receptor antagonist (ARB) used to treat hypertension and heart failure.

Used for the treatment of hypertension and heart failure .

Fimanta is also used to associated treatment for these conditions: Hypertension,Essential

How Fimanta works

Angiotensin II activates AR1 leading to vasoconstriction and increased noradrenaline release which further increases vasoconstriction via action at α1-adrenergic receptors . It also stimulates secretion of aldosterone which acts to increase sodium and water reabsorption in the renal tubules . Fimanta bind to and antagonizes AR1 preventing vasoconstriction and reducing aldosterone secretion to increase natriuresis leading to a reduction in blood volume. Together these effects produce an anti-hypertensive effect.

Elimination Route

Tmax is 0.5-1.3 h .

Half Life

The half life of elimination is 7-10 h .

Elimination Route

Most is eliminated unchangd in bile with less than 3% in the urine .

Innovators Monograph

You find simplified version here Fimanta

*** Taking medicines without doctor's advice can cause long-term problems.
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