Flogovital
Flogovital Uses, Dosage, Side Effects, Food Interaction and all others data.
Flogovital is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
Flogovital, a nonsteroidal anti-inflammatory fenamate, is a Ca2+-activated Cl- channel blocker.
Trade Name | Flogovital |
Generic | Niflumic acid |
Niflumic acid Other Names | Acide niflumique, Acido niflumico, Acidum niflumicum, Niflumic acid |
Type | |
Formula | C13H9F3N2O2 |
Weight | Average: 282.218 Monoisotopic: 282.061612157 |
Protein binding | 90% bound to plasma proteins. |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | Argentina |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Flogovital is a cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma.
Used in the treatment of rheumatoid arthritis.
Flogovital is also used to associated treatment for these conditions: Inflammation, Pain, Inflammatory, Postoperative Inflammatory Response
How Flogovital works
Flogovital is able to inhibit both phospholipase A2 as well as COX-2, thereby acting as an antiinflamatory and pain reduction agent.
Toxicity
Oral, mouse: LD50 = 350 mg/kg; Oral, rat: LD50 = 250 mg/kg
Elimination Route
Well absorbed following oral administration.
Half Life
2.5 hours
Innovators Monograph
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