Freon 218

Freon 218 Uses, Dosage, Side Effects, Food Interaction and all others data.

Freon 218, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Freon 218 enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.

Freon 218, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. It provide contrast enhancement of the endocardial borders during echocardiography. The perflutren lipid microspheres exhibit lower acoustic impedance than blood and enhance the intrinsic backscatter of blood.

Freon 218
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
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Interaction With other Medicine
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Trade Name	Freon 218
Availability	Prescription only
Generic	Perflutren
Perflutren Other Names	Freon 218, Octafluoropropane, Octafluorpropan, Oktafluorpropan, Perfluoropropane, Perflutren, Perflutreno
Related Drugs	Definity, Optison
Type
Formula	C₃F₈
Weight	Average: 188.0193 Monoisotopic: 187.98722564
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Freon 218 is a diagnostic medication to improve contrast during echocardiograms.

Used as an ultrasound contrast imaging in cardiology and radiology.

How Freon 218 works

Freon 218 is comprised of gas-filled microspheres that are injected or infused into the body. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Freon 218 enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.

Toxicity

There is new temporal evidence that perflutren may be associated with new-onset seizure activity following perflutren microbubble contrast injection during dobutamine-atropine stress echocardiography. [PMID: 23432576]