Fucidin Leo
Fucidin Leo Uses, Dosage, Side Effects, Food Interaction and all others data.
Fucidin Leo, an antibiotic derived from Fusidium coccineum, exerts powerful activity against a number of gram-positive organisms. Staphylococci, including the strains resistant to penicillin or other antibiotics, are particularly susceptible to Fucidin Leo. The therapeutic efficacy of topically applied Fucidin Leo is due partly to the pronounced antibacterial activity of Fucidin Leo against the organisms responsible for skin infection and partly to the unique ability of this antibiotic to penetrate intact skin.
Fusidic Acid is an anti-microbial agent that acts as an inhibitor of protein synthesis in the microorganism. It interferes with the translocation step by stabilizing the ribosome-guanosine dephosphate elongation factor G-complex. This prevents binding of aminoacyl t-RNA to the ribosome and thereafter stops transfer of additional amino acids to the growing polypeptide.
Fusidic acid inhibits bacterial protein synthesis by interfering with amino acid transfer from aminoacyl-tRNA to protein on the ribosomes.
Fusidicacidinhibitsbacterialproteinsynthesisbyinterferingwithaminoacidtransferfromaminoacyl-tRNAtoproteinontheribosomes.
| Trade Name | Fucidin Leo |
| Generic | Sodium Fusidate |
| Weight | 2% |
| Type | Cream, Ointment |
| Therapeutic Class | Other antibiotic |
| Manufacturer | Leo Pharmaceutical Ltd, Denmark |
| Available Country | Bangladesh |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Fucidin Leo Ointment is used for treatment of skin infections caused by Staphylococci, Streptococci, Corynebacterium minutissimum and other Fusidate sensitive organisms. The most important indications being: impetigo, boils, abscess, varicose ulcers, skin grafts, hidradenitis, infected wounds, sycosis barbae, paronychia, folliculitis, carbuncles and erythrasma.
Treatment of infections caused by susceptible organisms especially Staph eg, osteomyelitis, septicaemia, endocarditis, superinfected cystic fibrosis, pneumonia, skin & soft tissue infections, surgical & traumatic wound infections.
Dosage
Fucidin Leo dosage
Fucidin Leo Ointment or cream is applied to the affected areas 2 to 3 times daily, generally for a period of 7 days. It can be used with or without a covering dressing. Caution should be observed when applying Fucidin Leo Ointment near the eye region as this preparation may cause irritation if it gets into the eye. No special dosage modifications or special precautions are required for children.
Adult:250-500 mg every 8 hourly
Skin & soft tissue infection: 250 mg twice daily.
Side Effects
Fucidin Leo Ointment is remarkably well tolerated, and there is an extremely low frequency of hypersensitivity reactions.
GI disturbances eg, dyspepsia, nausea, vomiting, epigastric pain, anorexia; jaundice & change of liver function.
Precaution
Hepatic impairment, biliary obstruction or disease. Monitor hepatic function periodically in patients on high or prolonged oral doses. Avoid during 3rd trimester of pregnancy. Lactation. Premature, jaundiced, acidotic or seriously ill neonates.
Caution should be observed when applying Fucidin Leo ointment in the eye region as this preparation may cause irritation upon contact with the eye.
Interaction
Drugs metabolized by CYP450 isoenzymes.
Contraindication
Known hypersensitivity to Fucidin Leo, severe hepatic failure.
Innovators Monograph
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FAQ
What is Fucidin Leo used for?
Fucidin Leo used to treat bone infections caused by this germ. It works by stopping the growth of the germs.Fucidin Leo is also prescribed for other infections caused by staphylococcal germs, such as some skin infections.
How safe is Fucidin Leo?
Don't use Fucidin Leo for longer than prescribed, or save it for treating future infections, unless instructed to by your doctor. Prolonged or repeated use of antibacterial medicines can cause skin reactions and may also result in the bacteria becoming resistant to the medicine.
What are the common side effects of Fucidin Leo?
The most common side effects of Fucidin Leo eye drops are dry, sore, itchy or stinging eyes. You may also get blurred vision.
Is Fucidin Leo safe during pregnancy?
No effects during pregnancy are anticipated, since systemic exposure to topically-applied Fucidin Leo is negligible. Topical Fucidin can be used during pregnancy.
Is Fucidin Leo safe during breastfeeding?
It's generally safe to use fusidic acid cream, ointment or eye drops while you're breastfeeding. If you're breastfeeding, take care when you put on Fucidin Leo cream or ointment.
Is Fucidin Leo good for skin infection?
It is used to treat various skin infections caused by certain kinds of bacteria. Such infections may include impetigo and secondary infections to burns or broken skin.
Is Fucidin Leo good for wounds?
Fucidin Leo made to be put directly on skin and wounds.
Is Fucidin Leo good for wounds?
Fucidin Leo ointment is made to be put directly on skin and wounds.
Does Fucidin Leo help pimples?
Topical Fucidin Leo is occasionally used as a treatment for acne vulgaris. As a treatment for acne, Fucidin Leo is often partially effective at improving acne symptoms.
Is good for fungal infection?
Fucidin Leo is not active against fungal skin infections.
When should I not use Fucidin Leo?
Fucidin Leo is not recommended in the following conditions: atrophic skin, cutaneous ulcer, acne vulgaris, fragile skin veins and perianal and genital pruritus.
How many days should I use Fucidin Leo?
Only use it for as long as your doctor has instructed you to. A course of treatment typically lasts for around seven days. You should not use the cream or ointment for longer than 10 days.
Is Fucidin Leo good for a rash?
Fucidin Leo used to treat mild to moderately severe atopic (allergic) dermatitis rashes.
How do I use Fucidin Leo?
Fucidin Leo is also prescribed for other infections caused by staphylococcal germs.
How many times a day can I use Fucidin Leo?
Fucidin Leo used usual to put on fusidic acid cream or ointment 3 or 4 times a day.
Does Fucidin Leo stop itching?
It reduces the swelling, redness and itching and so helps prevent scratching that can further irritate the skin.
How should I use Fucidin Leo?
Apply a small amount to the affected area 2 to 3 times daily for 7 to 14 days. If your doctor has directed you to cover the lesion with a gauze dressing, you may be directed to apply the medication only 1 or 2 times daily.
What happen If I missed Fucidin Leo?
If you miss a dose, apply it as soon as remembered; do not apply it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not double-up the dose to catch up.
What happen If I overdose of Fucidin Leo?
If overdose is suspected, contact your local poison control center or emergency room immediately. This medicine may be harmful if swallowed.
