G-Chloramphenicol Ophthalmic Solution 0.5% Uses, Dosage, Side Effects and more

G-Chloramphenicol Ophthalmic Solution 0.5% Uses, Dosage, Side Effects, Food Interaction and all others data.

Table Of contents

• G-Chloramphenicol Ophthalmic Solution 0.5%
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	G-Chloramphenicol Ophthalmic Solution 0.5%
Generic	Chloramphenicol (Ophthalmic)
Weight	0.5%
Type	Ophthalmic Solution
Therapeutic Class	Ear Anti-Infectives & Antiseptics, Eye Anti-Infectives & Antiseptics, Macrolides
Manufacturer	Gonoshasthaya Pharma Ltd.
Available Country	Bangladesh
Last Updated:	January 7, 2025 at 1:49 am

Uses

Chloramphenicol is indicated for the treatment of ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol-susceptible organisms. Such as Staphylococcus aureus, Streptococcus pneumoniae, E.coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species.

Dosage

G-Chloramphenicol Ophthalmic Solution 0.5% dosage

Adult and Children: Instill 1 or 2 drops in the conjunctival sac 4-6 times per day for the first 72 hours and then every 4 hours thereafter. Treatment should be continued for approximately 7 days, but should not be continued for more than 3 weeks without re-evaluation by the physician.

Side Effects

The systemic adverse reaction has not been observed within short-term topical use of Chloramphenicol. The most frequently reported adverse reactions have been burning, stinging, conjunctival hyperemia, blood dyscrasia, allergic or inflammatory reactions, vesicular and maculopapular dermatitis.

Precaution

Chloramphenicol ophthalmic solution should never be given for minor infections or for prophylaxis. Repeated course and prolonged treatment should be avoided. Blood dyscrasias (granulocytopenia, thrombocytopenia and moderate anaemia) may occur after prolonged ophthalmic use.

Interaction

Chymotrypsin may be inhibited if given simultaneously with Chloramphenicol.

Pregnancy & Breastfeeding use

Safety for use in pregnancy and lactation has not been established. Therefore, use only when considered essential by the physicians.

Contraindication

It is contraindicated in individuals with a history of hypersensitivity to Chloramphenicol or any ingredients of the preparation.

Acute Overdose

Accidental ingestion of the medicine is unlikely to cause any toxicity due to low content of antibiotic.

Storage Condition

Store in a cool (between 2°C-8°C) and dry place, protect from light, keep out of reach of children. Do not touch the dropper tip to the surface since this may contaminate the solution. Do not use after 30 days of the first opening.

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