Guaiacol

Guaiacol Uses, Dosage, Side Effects, Food Interaction and all others data.

Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma.

Trade Name Guaiacol
Generic Guaiacol
Guaiacol Other Names 2-methoxyphenol, Guaiacol, o-guaiacol, o-hydroxyanisole, o-Methoxyphenol, Pyrocatechol monomethyl ether, Pyroguaiac acid
Type
Formula C7H8O2
Weight Average: 124.139
Monoisotopic: 124.052429498
Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Guaiacol
Guaiacol

Uses

It is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a potent scavenger of reactive oxygen radicals and its radical scavenging activity may be associated with its effect on cell proliferation.

Guaiacol is also used to associated treatment for these conditions: Productive cough, Chest congestion, Dry socket syndrome, Airway secretion clearance therapy

Food Interaction

No interactions found.

Elimination Route

In rats, guaiacol is rapidly absorbed, being present in the blood 5 minutes after oral administration, and reaching its peak plasma concentration in about 10 minutes. Its elimination from the blood is usually as rapid.

Elimination Route

Excreted by rabbits in combined form with sulfate (15%) and glucuronic acid (72%).

Innovators Monograph

You find simplified version here Guaiacol

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0002448
http://classyfire.wishartlab.com/tax_nodes/C0000134
http://classyfire.wishartlab.com/tax_nodes/C0000190
http://classyfire.wishartlab.com/tax_nodes/C0000190
http://classyfire.wishartlab.com/tax_nodes/C0004742
http://classyfire.wishartlab.com/tax_nodes/C0004113
http://classyfire.wishartlab.com/tax_nodes/C0000138
http://classyfire.wishartlab.com/tax_nodes/C0000128
http://classyfire.wishartlab.com/tax_nodes/C0004647
http://classyfire.wishartlab.com/tax_nodes/C0004646
http://classyfire.wishartlab.com/tax_nodes/C0004150
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:28591
http://metacyc.org/META/new-image?type=COMPOUND&object=CPD-400
http://www.hmdb.ca/metabolites/HMDB0001398
http://www.genome.jp/dbget-bin/www_bget?drug:D00117
http://www.genome.jp/dbget-bin/www_bget?cpd:C01502
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=460
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=347827973
https://www.chemspider.com/Chemical-Structure.447.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240369
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=5031
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=28591
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL13766
https://zinc.docking.org/substances/ZINC000013512224
https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/JZ3
https://en.wikipedia.org/wiki/Guaiacol
*** Taking medicines without doctor's advice can cause long-term problems.
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