O-hydroxyanisole
O-hydroxyanisole Uses, Dosage, Side Effects, Food Interaction and all others data.
O-hydroxyanisole is an agent thought to have disinfectant properties and used as an expectorant. O-hydroxyanisole is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. O-hydroxyanisole is also present in wood smoke, as a product of pyrolysis of lignin. O-hydroxyanisole has been found in the urine of patients with neuroblastoma and pheochromocytoma.
| Trade Name | O-hydroxyanisole |
| Generic | Guaiacol |
| Guaiacol Other Names | 2-methoxyphenol, Guaiacol, o-guaiacol, o-hydroxyanisole, o-Methoxyphenol, Pyrocatechol monomethyl ether, Pyroguaiac acid |
| Type | |
| Formula | C7H8O2 |
| Weight | Average: 124.139 Monoisotopic: 124.052429498 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
It is used medicinally as an expectorant, antiseptic, and local anesthetic. O-hydroxyanisole is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a potent scavenger of reactive oxygen radicals and its radical scavenging activity may be associated with its effect on cell proliferation.
O-hydroxyanisole is also used to associated treatment for these conditions: Productive cough, Chest congestion, Dry socket syndrome, Airway secretion clearance therapy
Food Interaction
No interactions found.Elimination Route
In rats, guaiacol is rapidly absorbed, being present in the blood 5 minutes after oral administration, and reaching its peak plasma concentration in about 10 minutes. Its elimination from the blood is usually as rapid.
Elimination Route
Excreted by rabbits in combined form with sulfate (15%) and glucuronic acid (72%).
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