Guna-Neural

Guna-Neural Uses, Dosage, Side Effects, Food Interaction and all others data.

Metenkefalin is an endogenous opioid and beta-endorphin. It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. Metenkefalin, along with tridecactide, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.

Table Of contents

• Guna-Neural
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Guna-Neural
Generic	Onitum napellus + metenkefalin + citrullus colocynthis fruit pulp + ferric phosphate + formica rufa + pseudognaphalium obtusifolium + iris versicolor root + kalmia latifolia leaf + neurotrophin-4 + paris quadrifolia
Type	Injection, solution
Therapeutic Class
Manufacturer
Available Country	United States
Last Updated:	September 19, 2023 at 7:00 am

Uses

Metenkefalin is an investigational endogenous opioid being studied for the treatment of COVID-19.

Metenkefalin is indicated in Bosnia for the treatment of relapsing-remitting multiple sclerosis.

How Guna-Neural works

Metenkefalin is an agonist of µ and δ opioid receptors. It also causes immunostimulation at low doses and immunosuppression at higher doses. Metenkefalin can also inhibit the production of aldosterone, deoxycorticosterone, and corticosterone. Unfortuneately, the mechanisms by which these effects occur have not been well described in the literature.

Toxicity

Data regarding overdoses of metenkefalin are not readily available. Animal overdose studies have not determined an LD₅₀.

Elimination Route

Metenkefalin reaches a C_max of 1266.14pg/mL, with a T_max of 0.16h, and an AUC of 360.64pg*h/mL.

Half Life

The half life of metenkefalin is 4.2-39 minutes.

Innovators Monograph

You find simplified version here Guna-Neural