Halazépam
Halazépam Uses, Dosage, Side Effects, Food Interaction and all others data.
Halazépam is a benzodiazepine derivative drug exerting anxiolytic, anticonvulsant, sedative, a muscle relaxing effects. It has been shown to be less toxic than chlordiazepoxide or diazepam. This drug is no longer marketed in the United States, and was withdrawn by Schering, its manufacturer, in 2009.
Trade Name | Halazépam |
Availability | Discontinued |
Generic | Halazepam |
Halazepam Other Names | Halazépam, Halazepam, Halazepamum |
Related Drugs | escitalopram, alprazolam, duloxetine, Lexapro, Xanax, Cymbalta |
Type | |
Formula | C17H12ClF3N2O |
Weight | Average: 352.738 Monoisotopic: 352.059025338 |
Groups | Approved, Illicit, Withdrawn |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Used to relieve anxiety, nervousness, and tension associated with anxiety disorders.
How Halazépam works
Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. Binding of GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell.
Food Interaction
[Moderate] GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents.
Use in combination may result in additive central nervous system depression and
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol.
Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
Halazépam Drug Interaction
Major: fentanyl, fentanylModerate: zolpidem, zolpidem, alprazolam, alprazolamUnknown: rabeprazole, rabeprazole, amphetamine / dextroamphetamine, amphetamine / dextroamphetamine, oxymetazoline nasal, oxymetazoline nasal, palonosetron, palonosetron, tryptophan, tryptophan, tiotropium, tiotropium, vortioxetine, vortioxetine
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