Hesperitin
Hesperitin Uses, Dosage, Side Effects, Food Interaction and all others data.
Hesperitin belongs to the flavanone class of flavonoids. Hesperitin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges.
Hesperitin is a cholesterol lowering flavanoid found in a number of citrus juices. It appears to reduce cholesteryl ester mass and inhibit apoB secretion by up to 80%. Hesperitin may have antioxidant, anti-inflammatory, anti-allergic, hypolipidemic, vasoprotective and anticarcinogenic actions.
| Trade Name | Hesperitin |
| Generic | Hesperetin |
| Hesperetin Other Names | Hesperitin |
| Type | |
| Formula | C16H14O6 |
| Weight | Average: 302.2788 Monoisotopic: 302.07903818 |
| Groups | Experimental |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase activity, as well as activity again.
How Hesperitin works
Hesperitin reduces or inhibits the activity of acyl-coenzyme A:cholesterol acyltransferase genes (ACAT1 and ACAT2) and it reduces microsomal triglyceride transfer protein (MTP) activity. Hesperitin also seems to upregulate the LDL receptor. This leads to the reduced assembly and secretion of apoB-containing lipoproteins and enhanced reuptake of those lipoproteins, thereby lowering cholesterol levels.
Innovators Monograph
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