Inocor

Inocor Uses, Dosage, Side Effects, Food Interaction and all others data.

Inocor (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.

Inocor is a positive inotropic cardiotonic with vasodilator properties, phosphodiesterase inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.

Inocor
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Inocor
Generic	Amrinone
Amrinone Other Names	Amrinona, Amrinone, Amrinonum, Inamrinone
Type
Formula	C₁₀H₉N₃O
Weight	Average: 187.198 Monoisotopic: 187.074561925
Protein binding	10 to 49%
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Inocor is a positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure.

Used in the treatment of congestive heart failure.

How Inocor works

Inocor is a phosphodiesterase inhibitor (PDE3), resulting in increased cAMP and cGMP which leads to an increase in the calcium influx like that caused by beta-agonists resulting in increased inotropic effect.

Volume of Distribution

1.2 L/kg [normal volunteers]

Half Life

5 to 8 hours

Elimination Route

The primary route of excretion in man is via the urine as both inamrinone and several metabolites (N-glycolyl, N-acetate, O-glucuronide and N-glucuronide).

Innovators Monograph

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