Ioflupanum (123I)

Ioflupanum (123I) Uses, Dosage, Side Effects, Food Interaction and all others data.

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.

iodine-123 labeled ioflupanebinds selectively to striatal presynaptic dopamine neurons by binding reversibly to presynaptic dopamine transporters.

Table Of contents

• Ioflupanum (123I)
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Ioflupanum (123I)
Generic	Ioflupane I-123
Ioflupane I-123 Other Names	123I-FP-CIT, 123I-Ioflupane, Iodine ioflupane (123I), Ioflupane (123I), Ioflupane I 123, Ioflupane I(123), Ioflupano (123I), Ioflupanum (123I)
Type
Formula	C18H23FINO2
Weight	Average: 427.291 Monoisotopic: 427.076880092
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Ioflupanum (123I) is a radiopharmaceutical used in single photon emission computed tomography (SPECT) brain imaging to help diagnose patients with suspected Parkinsonian syndromes.

Ioflupanum (123I) is a SPECT (single photon emission computerized tomography) agent used to distinguish between Parkinson’s syndrome tremors and essential tremor.

Ioflupanum (123I) is also used to associated treatment for these conditions: Parkinsonian Syndromes

How Ioflupanum (123I) works

Iodine-123 labeled ioflupane binds to presynaptic dopamine transporters. When Iodine-123 decays, a gammay ray is emmitted and detected through SPECT.

Food Interaction

• Take with or without food.

Volume of Distribution

Compared to the entire brain, about 30% of radioactivity is taken up by the striatum.

Elimination Route

Absorption is 100% because administered I.V.

Half Life

Half life is 13.2 hours.

Elimination Route

About 60% is excreted in the urine and 14% in the feces after 48 hours.

Innovators Monograph

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