Капреомицин-ДЕКО

Капреомицин-ДЕКО Uses, Dosage, Side Effects, Food Interaction and all others data.

Cyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus.

Капреомицин-ДЕКО is a member of the aminoglycoside family of antibiotics. These antibiotics have the ability to kill a wide variety of bacteria, including bacteria responsible for causing tuberculosis (TB).

Table Of contents

• Капреомицин-ДЕКО
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Капреомицин-ДЕКО
Availability	Discontinued
Generic	Capreomycin
Capreomycin Other Names	Capreomicina, Capreomycin
Related Drugs	ciprofloxacin, levofloxacin, Levaquin, rifampin
Type
Formula	C50H88N28O15
Weight	Average: 1321.4123 Monoisotopic: 1320.698394286
Groups	Approved
Therapeutic Class
Manufacturer
Available Country	Russia
Last Updated:	September 19, 2023 at 7:00 am

Uses

Капреомицин-ДЕКО is an aminoglycoside antibiotic used as an adjunct drug in tuberculosis.

Used in the treatment of tuberculosis in combination with other drugs.

Капреомицин-ДЕКО is also used to associated treatment for these conditions: Tuberculosis (TB)

How Капреомицин-ДЕКО works

Little is known about capreomycin's exact mechanism of action, but it is thought to inhibit protein synthesis by binding to the 70S ribosomal unit. Капреомицин-ДЕКО also binds to components in the bacterial cell which result in the production of abnormal proteins. These proteins are necessary for the bacteria's survival. Therefore the production of these abnormal proteins is ultimately fatal to the bacteria.

Toxicity

Hypokalemia, hypocalcemia, hypomagnesemia, and an electrolyte disturbance resembling Bartter's syndrome have been reported to occur in patients with capreomycin toxicity. The subcutaneous median lethal dose (LD₅₀) in mice was 514 mg/kg.

Food Interaction

No interactions found.

Капреомицин-ДЕКО Drug Interaction

Major: RHO Immunoglobulin , RHO Immunoglobulin Moderate: ciprofloxacin, ciprofloxacinUnknown: 5-hydroxytryptophan, 5-hydroxytryptophan, vitamin a & d topical, vitamin a & d topical, acetylcysteine, acetylcysteine, aspirin, aspirin, glucose, glucose, heparin, heparin, acetaminophen, acetaminophen, cholecalciferol, cholecalciferol

Капреомицин-ДЕКО Disease Interaction

Major: hearing loss, renal dysfunctionModerate: hypokalemia, liver impairment, magnesium and calcium imbalance

Elimination Route

Not absorbed in significant quantities from the gastrointestinal tract and must be administered parenterally.

Elimination Route

When a 1–g dose of capreomycin was given intramuscularly to normal volunteers, 52% was excreted in the urine within 12 hours.

Innovators Monograph

You find simplified version here Капреомицин-ДЕКО