L-Alanosine Uses, Dosage, Side Effects and more
An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
| Attribute | Details |
|---|---|
| Trade Name | L-Alanosine |
| Generic | Alanosine |
| Alanosine Other Names | Alanosina, Alanosine, Alanosinum, L-Alanosine |
| Type | |
| Formula | C3H7N3O4 |
| Weight | Average: 149.1054 Monoisotopic: 149.043655727 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in brain cancer and cancer/tumors (unspecified).
How L-Alanosine works
L-alanosine inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate, an intermediate in purine metabolism. L-alanosine-induced disruption of de novo purine biosynthesis is potentiated by methylthioadenosine phosphorylase (MTAP) deficiency.
