Levorin

Levorin Uses, Dosage, Side Effects, Food Interaction and all others data.

Levorin is an antibiotic obtained from a streptomyces (Streptomyces griseus) and active against some fungi of the genus Candida (C. albicans). Levorin is administered intravaginally in the treatment of vulvovaginal candidiasis.

Levorin is a polyene antifungal antibiotic produced by a strain of Streptomyces griseus. It is especially effective against Candida albicans (more effective than amphotericin B), and is administered intravaginally in the treatment of vulvovaginal candidiasis.

Table Of contents

• Levorin
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Levorin
Generic	Candicidin
Candicidin Other Names	Candicidin, Candicidina, Candicidine, Candicidinum, Candizidin, Levorin, Levorina, Levorine, Levorinum
Type
Formula	C59H84N2O18
Weight	Average: 1109.317 Monoisotopic: 1108.571913873
Groups	Approved, Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Used in the topical treatment of vulvovaginal candidiasis.

How Levorin works

Ergosterol, the principal sterol in the fungal cytoplasmic membrane, is the target site of action of Levorin. Levorin binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death. There is some evidence that the binding site in the cell wall may be to fatty acids or fatty acid esters and that this binding capacity must be satisfied before candicidin can bring about its lethal effect by binding to sterol in the cell membrane.

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