Locorten

Locorten Uses, Dosage, Side Effects, Food Interaction and all others data.

Locorten is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.

Locorten pivalate is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.

Locorten
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Uses during Pregnancy
Uses during Breastfeeding
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Trade Name	Locorten
Generic	Flumethasone
Flumethasone Other Names	Flumetasona, Flumétasone, Flumetasone, Flumetasonum, Flumethasone
Type
Formula	C₂₂H₂₈F₂O₅
Weight	Average: 410.458 Monoisotopic: 410.190480328
Groups	Approved, Vet approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Locorten is a corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions.

For the treatment of contact dermatitis, atopic dermatitis, exczema, psoriasis, diaper rash and other skin conditions

Locorten is also used to associated treatment for these conditions: Atopic Dermatitis (AD), Atopic Dermatitis (AD) of the external ear canal, Cradle Cap, Dermatitis, Dermatosis, Discoid Lupus Erythematosus (DLE), Infantile Eczema, Inflammatory Skin Disease, Intertrigo, Lichen Planus (LP), Neurodermatitis, Otitis Externa, Psoriasis Vulgaris (Plaque Psoriasis), Radiodermatitis, Solar erythema, Corticosteroid-responsive dermatoses, Intertriginous erythema of the anogenital, Otomycosis caused by Aspergillus niger, Resistant to other corticosteroids Dermatosis

How Locorten works

Locorten is a glucocorticoid receptor agonist. This complex binds to the nucleus causing a variety of genetic activation and repressions. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. Locorten binds to plasma transcortin, and it becomes active when it is not bound to transcortin.