Mafenide acetate ointment 10%

Mafenide acetate ointment 10% Uses, Dosage, Side Effects, Food Interaction and all others data.

Mafenide acetate ointment 10% is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns.

Trade Name Mafenide acetate ointment 10%
Availability Prescription only
Generic Mafenide
Mafenide Other Names 4-Homosufanilamide, Bensulfamide, Mafenide, Maphenidum
Related Drugs lidocaine topical, vancomycin, gentamicin, tobramycin, Silvadene, Garamycin
Type
Formula C7H10N2O2S
Weight Average: 186.232
Monoisotopic: 186.046298264
Groups Approved, Vet approved
Therapeutic Class
Manufacturer
Available Country Russia
Last Updated: September 19, 2023 at 7:00 am
Mafenide acetate ointment 10%
Mafenide acetate ointment 10%

Uses

Mafenide acetate ointment 10% is an antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.

Indicated for use as an adjunctive topical antimicrobial agent to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.

Mafenide acetate ointment 10% is also used to associated treatment for these conditions: Second Degree Burns, Third Degree Burns

How Mafenide acetate ointment 10% works

The precise mechanism of mafenide is unknown. However, mafenide reduces the bacterial population in the avascular burn tissue and promotes spontaneous heeling of deep burns.

Toxicity

Since mafenide is metabolized to a carbonic anhydrase inhibitor, metabolic acidosis could occur.

Food Interaction

No interactions found.

Mafenide acetate ointment 10% Disease Interaction

Moderate: acid/base balance, hemolytic anemia/DIC

Elimination Route

Mafenide acetate ointment 10% is absorbed through devascularized areas into the systemic circulation following topical administration.

Elimination Route

Renal—Metabolite rapidly excreted in urine in high concentrations; however, the parent compound has not been detected in urine.

Innovators Monograph

You find simplified version here Mafenide acetate ointment 10%

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https://en.wikipedia.org/wiki/Mafenide
*** Taking medicines without doctor's advice can cause long-term problems.
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