Méthoxamine
Méthoxamine Uses, Dosage, Side Effects, Food Interaction and all others data.
An alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.
Méthoxamine is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Méthoxamine is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Méthoxamine acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.
Trade Name | Méthoxamine |
Availability | Discontinued |
Generic | Methoxamine |
Methoxamine Other Names | Méthoxamédrine, Methoxamin, Méthoxamine, Methoxamine, Methoxaminum, Metossamina, Metoxamina, Pseudomethoxamine |
Type | |
Formula | C11H17NO3 |
Weight | Average: 211.2576 Monoisotopic: 211.120843415 |
Protein binding | Low |
Groups | Approved, Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Méthoxamine is an alpha adrenergic agonist used to treat hypotension.
Indicated for the treatment and management of hypotension.
How Méthoxamine works
Méthoxamine acts through peripheral vasoconstriction by acting as a pure alpha-1 adrenergic receptor agonist, consequently increasing systemic blood pressure (both systolic and diastolic).
Méthoxamine Drug Interaction
Moderate: albuterol, albuterol, milnacipran, milnacipranUnknown: contained in alcoholic beverages , contained in alcoholic beverages , aspirin, aspirin, lorazepam, lorazepam, tamsulosin, tamsulosin, fluticasone nasal, fluticasone nasal, mirabegron, mirabegron, cholecalciferol, cholecalciferol, cetirizine, cetirizine
Méthoxamine Disease Interaction
Innovators Monograph
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