Methoxaminum

Methoxaminum Uses, Dosage, Side Effects, Food Interaction and all others data.

An alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.

Methoxaminum is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Methoxaminum is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Methoxaminum acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.

Table Of contents

• Methoxaminum
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Methoxaminum
Availability	Discontinued
Generic	Methoxamine
Methoxamine Other Names	Méthoxamédrine, Methoxamin, Méthoxamine, Methoxamine, Methoxaminum, Metossamina, Metoxamina, Pseudomethoxamine
Type
Formula	C11H17NO3
Weight	Average: 211.2576 Monoisotopic: 211.120843415
Protein binding	Low
Groups	Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Methoxaminum is an alpha adrenergic agonist used to treat hypotension.

Indicated for the treatment and management of hypotension.

How Methoxaminum works

Methoxaminum acts through peripheral vasoconstriction by acting as a pure alpha-1 adrenergic receptor agonist, consequently increasing systemic blood pressure (both systolic and diastolic).

Methoxaminum Drug Interaction

Moderate: albuterol, albuterol, milnacipran, milnacipranUnknown: contained in alcoholic beverages , contained in alcoholic beverages , aspirin, aspirin, lorazepam, lorazepam, tamsulosin, tamsulosin, fluticasone nasal, fluticasone nasal, mirabegron, mirabegron, cholecalciferol, cholecalciferol, cetirizine, cetirizine

Methoxaminum Disease Interaction

Major: dehydrationModerate: acidosis

Innovators Monograph

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