Mikamycin A
Mikamycin A Uses, Dosage, Side Effects, Food Interaction and all others data.
Pristinamycin IIA is a macrolide antibiotic, a member of the streptogramin A group of antibiotics, and one component of pristinamycin. It is produced by Streptomyces graminofaciens and other bacteria.
| Trade Name | Mikamycin A |
| Generic | Virginiamycin M1 |
| Virginiamycin M1 Other Names | Mikamycin A, Ostreogrycin A, Pristinamycin IIA, Streptogramin A, Virginiamycin factor M1, Virginiamycin M1 |
| Type | |
| Formula | C28H35N3O7 |
| Weight | Average: 525.5934 Monoisotopic: 525.247500489 |
| Groups | Experimental |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of bacterial infections.
How Mikamycin A works
Mikamycin A is a macrocyclic lactone antibiotic that acts syngeristically with the structurally unrelated cyclic depsipeptides more commonly known as the virginiamycins B (ostreogrycin B or streptogramin B) and S to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Mikamycin A has proven to be highly active against Gram positive bacteria, particularly methicillin-resistant S. aureus.
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