MVA-Muc1-IL2

MVA-Muc1-IL2 Uses, Dosage, Side Effects, Food Interaction and all others data.

A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities. Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory activity against antigens. Vaccination with MVA-MUC1-IL2 vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing MUC1, a tumor associated antigen, resulting in tumor cell lysis. Expression of IL-2 augments the specific CTL response against MUC1 expressing cells.

Trade Name MVA-Muc1-IL2
Generic TG4010
TG4010 Other Names MVA-Muc1-IL2
Type
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
MVA-Muc1-IL2
MVA-Muc1-IL2

Uses

Investigated for use/treatment in breast cancer, renal cell carcinoma, prostate cancer, and lung cancer.

Innovators Monograph

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