Nereflun

Nereflun Uses, Dosage, Side Effects, Food Interaction and all others data.

Nereflun (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.

Nereflun is a synthetic corticosteroid. It is administered either as an oral metered-dose inhaler for the treatment of asthma or as a nasal spray for treating allergic rhinitis. Corticosteroids are naturally occurring hormones that prevent or suppress inflammation and immune responses. When given as an intranasal spray, flunisolide reduces watery nasal discharge (rhinorrhea), nasal congestion, postnasal drip, sneezing, and itching oat the back of the throat that are common allergic symptoms.

Nereflun
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
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Interaction With other Medicine
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Trade Name	Nereflun
Availability	Discontinued
Generic	Flunisolide
Flunisolide Other Names	Flunisolida, Flunisolide, Flunisolidum
Related Drugs	Trelegy Ellipta, prednisone, Breo Ellipta, Xopenex, Dulera, Atrovent, Fasenra
Type
Formula	C₂₄H₃₁FO₆
Weight	Average: 434.4977 Monoisotopic: 434.210466929
Protein binding	Approximately 40% after oral inhalation
Groups	Approved, Investigational
Therapeutic Class
Manufacturer
Available Country	Italy
Last Updated:	September 19, 2023 at 7:00 am

Uses

Nereflun is an inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.

For the maintenance treatment of asthma as a prophylactic therapy.

Nereflun is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Asthma

How Nereflun works

Nereflun is a glucocorticoid receptor agonist. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. Nereflun binds to plasma transcortin, and it becomes active when it is not bound to transcortin.