Nordefrin

Nordefrin Uses, Dosage, Side Effects, Food Interaction and all others data.

Nordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.

Nordefrin is a sympathomimetic amine used as a vasoconstrictor in local anesthetic solutions. It has pharmacologic activity similar to that of Epinephrine but it is more stable than Epinephrine. In equal concentrations, Nordefrin is less potent than Epinephrine in raising blood pressure, and as a vasoconstrictor.

Trade Name Nordefrin
Generic Levonordefrin
Levonordefrin Other Names alpha-Methylnoradrenaline, Corbadrina, Corbadrine, Corbadrinum, L-Nordefrin, Levonordefrin, Neo-cobefrin
Type
Formula C9H13NO3
Weight Average: 183.2044
Monoisotopic: 183.089543287
Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Nordefrin
Nordefrin

Uses

Nordefrin is a topical sympathomimetic amine found in local anesthetic products that is used for nasal decongestion or vasoconstriction during dental procedures.

Used as a topical nasal decongestant and vasoconstrictor in dentistry.

How Nordefrin works

It is designed to mimic the molecular shape of adrenaline. It binds to alpha-adrenergic receptors in the nasal mucosa. Here it can, therefore, cause vasoconstriction.

Food Interaction

No interactions found.

Innovators Monograph

You find simplified version here Nordefrin

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0002448
http://classyfire.wishartlab.com/tax_nodes/C0002279
http://classyfire.wishartlab.com/tax_nodes/C0002811
http://classyfire.wishartlab.com/tax_nodes/C0002811
http://classyfire.wishartlab.com/tax_nodes/C0000135
http://classyfire.wishartlab.com/tax_nodes/C0003899
http://classyfire.wishartlab.com/tax_nodes/C0004647
http://classyfire.wishartlab.com/tax_nodes/C0004646
http://classyfire.wishartlab.com/tax_nodes/C0001661
http://classyfire.wishartlab.com/tax_nodes/C0001897
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0000469
http://classyfire.wishartlab.com/tax_nodes/C0004150
http://classyfire.wishartlab.com/tax_nodes/C0003073
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:10304
http://www.hmdb.ca/metabolites/HMDB0015652
http://www.genome.jp/dbget-bin/www_bget?drug:D02388
http://www.genome.jp/dbget-bin/www_bget?cpd:C11768
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=164739
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=99443259
https://www.chemspider.com/Chemical-Structure.144416.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50223426
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=132889
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=10304
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL677
https://zinc.docking.org/substances/ZINC000000034157
http://www.pharmgkb.org/drug/PA165958380
http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=508
https://en.wikipedia.org/wiki/Levonordefrin
*** Taking medicines without doctor's advice can cause long-term problems.
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