Normal Saline (denis)
Normal Saline (denis) Uses, Dosage, Side Effects, Food Interaction and all others data.
Normal Saline (denis) is the major extracellular cation. It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes. It is also used as diluents for infusion of compatible drug additives.
Sodium, the major cation of the extracellular fluid, functions primarily in the control of water distribution, fluid balance, and osmotic pressure of body fluids. Sodium is also associated with chloride and bicarbonate in the regulation of the acid-base equilibrium of body fluid.Chloride, the major extracellular anion, closely follows the metabolism of sodium, and changes in the acid-base balance of the body are reflected by changes in the chloride concentration.
| Trade Name | Normal Saline (denis) |
| Generic | Sodium chloride |
| Sodium chloride Other Names | Cloruro sódico, Natriumchlorid, Natrum muriaticum, Sodium chloride |
| Type | Solution For Infusion |
| Formula | ClNa |
| Weight | Average: 58.443 Monoisotopic: 57.958622382 |
| Protein binding | Sodium is not bound by plasma proteins. |
| Groups | Approved, Vet approved |
| Therapeutic Class | Nasal Decongestants & Other Nasal Preparations |
| Manufacturer | Denis Chem Lab Ltd |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Sodium Chloride Nasal Drops is used for dry nasal membranes including dry nose resulting from cold and allergy medications. It moistens dry nasal passages from dry climates or from airplane travel, may help dissolve mucus from study noses and clears the nose after surgery. This sterile saline solution is also used to cleanse various parts of the body (wounds, body cavities) and medical equipment (e.g., bandages, catheters, drainage tubes). It is also used as a mixing solution (diluent) for other medications used to irrigate the body (e.g., bacitracin, polymyxin).
Normal Saline (denis) is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Corneal Edema, Dehydration, Dehydration Hypertonic, Fluid Loss, Hemodilution, Hypertension Intracranial, Hypokalemia, Hyponatremia, Hypotonic Dehydration, Hypovolaemia, Increased Intra Ocular Pressure (IOP), Inflammation of the Nasal Mucosa, Isotonic Dehydration, Metabolic Acidosis, Nasal Congestion, Nasal irritation, Oliguria caused by Acute Renal Failure (ARF), Potassium deficiency, Sinusitis, Skin Irritation, Sodium Depletion, Dryness of the nose, Hypochloremic state, Mild Metabolic acidosis, Mild, moderate Metabolic Acidosis, Electrolyte replacement, Fluid replacement therapy, Heart-Lung-Machine, Oral rehydration therapy, Parenteral Nutrition, Parenteral rehydration therapy, Peritoneal dialysis therapy, Plasma Volume Replacement, Regional Citrate Anticoagulation (RCA), Renal Replacement Therapies, Urine alkalinization therapy, Wound irrigation therapy, Ear wax removal, Fluid and electrolyte maintenance therapy, Increased renal excretion of toxic substances, Maintenance source of fluid and electrolytes, Parenteral drug administration, Reducing brain mass
How Normal Saline (denis) works
Sodium and chloride — major electrolytes of the fluid compartment outside of cells (i.e., extracellular) — work together to control extracellular volume and blood pressure. Disturbances in sodium concentrations in the extracellular fluid are associated with disorders of water balance.
Dosage
Normal Saline (denis) dosage
Infants, children & adults: 2-6 drops into each nostril as needed daily
Use in Children: Safe for pediatrics
Side Effects
No side Effects are expected to occur. However stinging, sneezing, increased nasal discharge, or salty taste may occur in some cases.
Toxicity
The rare inadvertent intravascular administration or rapid intravascular absorption of hypertonic sodium chloride can cause a shift of tissue fluids into the vascular bed, resulting in hypervolemia, electrolyte disturbances, circulatory failure, pulmonary embolism, or augmented hypertension.
Food Interaction
No interactions found.Volume of Distribution
The volume of distribution is 0.64 L/kg.
Elimination Route
Absorption of sodium in the small intestine plays an important role in the absorption of chloride, amino acids, glucose, and water. Chloride, in the form of hydrochloric acid (HCl), is also an important component of gastric juice, which aids the digestion and absorption of many nutrients.
Half Life
17 minutes
Elimination Route
Substantially excreted by the kidneys.
Pregnancy & Breastfeeding use
It is unknown if this medication passes into breast milk. Consult with your doctor before breast-feeding.
Contraindication
Tell your doctor about your medical history, especially of heart problems (e.g., congestive heart failure), lung problems (pulmonary edema), kidney problems, low levels of potassium (hypokalemia), high levels of sodium (hypernatremia), and any allergies.
Innovators Monograph
You find simplified version here Normal Saline (denis)
FAQ
What is Normal Saline (denis) used for?
Normal Saline (denis) used to treat or prevent sodium loss caused by dehydration, excessive sweating, or other causes.Normal Saline (denis) also plays a part in nerve impulses and muscle contractions.
How safe is Normal Saline (denis)?
Normal Saline (denis) generally recognized as safe” (GRAS) ingredient. A “GRAS” substance is one that has a long history of safe, common use in foods, or that is determined to be safe, for the intended use, based on proven science.
What are the common side effects of Normal Saline (denis)?
The common side effects of Normal Saline (denis) are include:
- Fast heartbeat
- fever
- hives, itching, or rash
- hoarseness
- irritation
- joint pain, stiffness, or swelling
- redness of the skin
- shortness of breath
- swelling of the eyelids, face, lips, hands, or feet
- tightness in the chest
- troubled breathing or swallowing
Is Normal Saline (denis) safe during pregnancy?
Normal Saline (denis) should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.
Is Normal Saline (denis) safe during breastfeeding?
It is not known whether sodium chloride passes into breast milk or if it could harm a nursing baby. Do not use Normal Saline (denis) without telling your doctor if you are breast-feeding a baby.
Can I drink alcohol with Normal Saline (denis)?
Chronic heavy drinking is known to elevate blood pressure.Normal Saline (denis) sensitivity also tends to raise blood pressure. New research indicates that withdrawal from heavy drinking may derange Normal Saline (denis) metabolism in such a way that a person's sodium sensitivity is increased, leading to higher blood pressure.
Is Normal Saline (denis) safe for skin?
Normal Saline (denis) when used in a shower soap can have many medicinal and healing benefits as it can help treat some skin conditions and help exfoliateNormal Saline (denis). should be one of the lowest on the ingredient list to avoid the drying effects on skin.
Can I drink Normal Saline (denis)?
Tke Normal Saline (denis) with a full glass (8 ounces) of water.
Is Normal Saline (denis) harmful to humans?
Normal Saline (denis) isn't a health hazard, but in excessive amounts it can irritate your eyes, skin, airways.
When is the best time to take Normal Saline (denis)?
Take tablets with or without food. Take with food if it causes an upset stomach.You may dissolve the tablet in water and drink.
How often can I take Normal Saline (denis) tablets?
Foe adults one tablet per day.For children se and dose must be determined by your doctor.
How does bransd affect the heart?
Too much salt can cause fluid to build up around the heart and lungs, making the heart work harder.
How many sodium tablets can I take a day?
We suggest people start with 1 or 2 tablets once or twice a day and increase according to the above factors to a maximum of 2 tablets four times a day (8 tablets in 24 hours).
Who should not take Normal Saline (denis)?
You should not take Normal Saline (denis) if you have ever had an allergic reaction to it, or if you have high sodium levels in your blood.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention.overdose symptoms may include nausea, vomiting, stomach cramps, diarrhea, fast or uneven heart rate, weakness, swelling in your hands or feet, feeling restless or irritable, slow breathing, feeling short of breath, or seizure (convulsions).
Why is Normal Saline (denis) in shower gel?
In cosmetics, it is often used as a thickener in shampoos and shower gels or in oral preparations to clean and eliminate odors
Is Normal Saline (denis) bad for humans?
Normal Saline (denis) toxicity has not been observed in humans except in the special case of impaired Normal Saline (denis) metabolism.
