Noscapinehydrochloride
Noscapinehydrochloride Uses, Dosage, Side Effects, Food Interaction and all others data.
| Trade Name | Noscapinehydrochloride |
| Generic | Noscapine |
| Noscapine Other Names | alpha-Narcotine, Noscapina, Noscapine, Noscapinum |
| Type | |
| Formula | C22H23NO7 |
| Weight | Average: 413.4205 Monoisotopic: 413.147452095 |
| Groups | Approved, Investigational |
| Therapeutic Class | |
| Manufacturer | Samenwerkende Apothekers Nederland |
| Available Country | Netherlands |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Noscapinehydrochloride is a non-sedating isoquinoline alkaloid used primarily for its antitussive properties.
Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma.
Noscapinehydrochloride is also used to associated treatment for these conditions: Common Cold, Cough, Respiratory Diseases, Airway secretion clearance therapy
How Noscapinehydrochloride works
Noscapinehydrochloride's antitussive effects appear to be primarily mediated by its sigma receptor agonist activity. Evidence for this mechanism is suggested by experimental evidence in rats. Pretreatment with rimcazole, a sigma specific antagonist, causes a dose-dependent reduction in antitussive activity of noscapine.
Innovators Monograph
You find simplified version here Noscapinehydrochloride
