Noxtal

Noxtal Uses, Dosage, Side Effects, Food Interaction and all others data.

Noxtal is a sedative-hypnotic thienodiazepine drug which is a benzodiazepine analog. It demonstrates anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant effects. Noxtal has similar effects to short-acting benzodiazepines such as triazolam. Noxtal is indicated for 2-4 weeks of treatment for severe or debilitating insomnia. Noxtal is an extremely potent drug and it is rapidly eliminated with an average half-life of 4.4 hours (range 3.6 - 7.9 hours).

Noxtal is not approved for sale in the UK, United States or Canada but is sold in the Netherlands, Germany, Spain, Belgium, Austria, Portugal, Israel, Italy and Japan.

Trade Name Noxtal
Generic Brotizolam
Brotizolam Other Names Brotizolam, Brotizolamum
Type
Formula C15H10BrClN4S
Weight Average: 393.689
Monoisotopic: 391.949807384
Protein binding

The mean value of the free fraction (%): 8.4 ± 0.7.

Groups Investigational, Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Noxtal
Noxtal

Uses

Noxtal is a benzodiazepine analogue with sedative-hypnotic properties used for short-term treatment of severe or debilitating insomnia.

Noxtal is indicated for 2-4 weeks in the treatment of severe or debilitating insomnia.

Noxtal is also used to associated treatment for these conditions: Insomnia

Volume of Distribution

0.63 l/kg.

Elimination Route

The plasma concentration profile of brotizolam can be described as a one compartmental open model with first-order absorption.

Half Life

4.4 hours.

Clearance

Total clearance: 109 ml/min.

Innovators Monograph

You find simplified version here Noxtal

*** Taking medicines without doctor's advice can cause long-term problems.
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