O-Cal
O-Cal Uses, Dosage, Side Effects, Food Interaction and all others data.
O-Cal contains Calcium Orotate, a calcium supplement with a functional amino acid chelating ligand - orotic acid. Orotic acid assists the transport of calcium through cellular membrane structures, facilitating the intracellular uptake of calcium, particularly in bone. Calcium Orotate also helps in the maintenance of healthy cartilage. Furthermore, Orotate is involved in the synthesis of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). Calcium Orotate has the ability to penetrate complex cell membranes and it can be metabolized in cartilage.
Trade Name | O-Cal |
Generic | Calcium Orotate Dihydrate |
Weight | 740mg |
Type | Tablet |
Therapeutic Class | Minerals in bone formation, Specific mineral preparations |
Manufacturer | Acme Laboratories Limited |
Available Country | Bangladesh |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
O-Cal is used -
1. To prevent or treat low blood calcium levels in people who do not
get enough calcium from diets.
2. To fulfill the calcium deficiency or meet extra need of calcium in
conditions like-
• Osteomalacia
• Rickets
• Latent tetany
• Postmenopausal osteoporosis
• Senile osteoporosis
• Juvenile osteoporosis
• Drug induced osteoporosis
(Phenytoin, Phenobarbital, or Prednisone)
• Pregnancy and lactation
• Premenstrual syndrome (PMS)
• Hypoparathyroidism
• Hip joint plastic surgery
3. Acts against a number of inflammatory diseases like -
• Arthritis
• Multiple sclerosis
• Spondylitis
4. Helps in controlling weight by suppressing the habit of frequent
appetite of chronic overeaters.
5. It is also beneficial in reducing the effects of mood swings.
6. Proved to be quite effective in cognitive enhancement.
7. Protects the heart by enhancing the efficiency of cardiac muscles.
Dosage
O-Cal dosage
Calcium Orotate 400 mg: As an addition to the daily diet, 2-3 tablets are usually recommended with meal, after meal or as directed by physician.
Calcium Orotate 740 mg: As an addition to the daily diet, 1-2 tablets are usually recommended with meal, after meal or as directed by physician.
Side Effects
Bloating and swelling in the abdomen are common side effects of Calcium Orotate. Constipation, nausea, vomiting, headache, increased thirst/ urination, may occur infrequently.
Precaution
Before taking calcium, precaution is needed if the patient has any allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Precaution is needed before using this product in kidney disease, kidney stones, little or no stomach acid (achlorhydria), heart disease, disease of the pancreas, a certain lung disease(sarcoidosis), difficulty absorbing nutrition from food (malabsorption syndrome).
Interaction
Calcium can decrease absorption of the following drugs when taken together with bisphosphonates, quinolone antibiotics, tetracycline antibiotics, levothyroxine, phenytoin and tiludronate disodium. Thiazide-type diuretics can interact with Calcium supplements, increasing the risks of hypercalcemia and hypercalciuria.
Pregnancy & Breastfeeding use
During pregnancy and lactation treatment with Calcium Orotate should always be under the direction of a physician. Women who are pregnant and breast feeding need more Calcium. Pregnancy related high blood pressure is a common and serious risk for women and their babies. Taking supplement of Calcium Orotate can help to reduce this risk.
Contraindication
Calcium Orotate is contraindicated in conditions like kidney stone, kidney disease, increased activity of the parathyroid gland, high amount of Calcium in urine & blood and extreme loss of body water.
Acute Overdose
Symptoms of over dose may include nausea/ vomiting, weight loss, loss of appetite, constipation, headache, weakness etc if any of the side effects become serious please talk with physician.
Storage Condition
Store below 30º C. Protect from light and moisture. Keep out of the reach of children.
Innovators Monograph
You find simplified version here O-Cal