Pamine

Pamine Uses, Dosage, Side Effects, Food Interaction and all others data.

Pamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Pamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.

Pamine bromide is an anticholinergic agent which possesses most of the pharmacologic actions of that drug class. These include reduction in volume and total acid content of gastric secretion, inhibition of gastrointestinal motility, inhibition of salivary excretion, dilation of the pupil and inhibition of accommodation with resulting blurring of vision. Large doses may result in tachycardia [Dailymed].

Trade Name	Pamine
Availability	Prescription only
Generic	Methscopolamine
Methscopolamine Other Names	Methylscopolamine
Related Drugs	famotidine, pantoprazole, Pepcid, Protonix, glycopyrrolate, Librax
Weight	2.5mg, 5mg,
Type	Oral tablet
Formula	C₁₈H₂₄NO₄
Weight	Average: 318.392 Monoisotopic: 318.169984677
Groups	Approved
Therapeutic Class
Manufacturer
Available Country	United States,
Last Updated:	September 19, 2023 at 7:00 am

Pamine Alcohol interaction

[Moderate] GENERALLY AVOID:

Use of anticholinergic agents with alcohol may result in sufficient impairment of attention so as to render driving and operating machinery more hazardous.

In addition, the potential for abuse may be increased with the combination.

The mechanism of interaction is not established but may involve additive depressant effects on the central nervous system.

No effect of oral propantheline or atropine on blood alcohol levels was observed in healthy volunteers when administered before ingestion of a standard ethanol load.

However, one study found impairment of attention in subjects given atropine 0.5 mg or glycopyrrolate 1 mg in combination with alcohol.

Alcohol should generally be avoided during therapy with anticholinergic agents.

Patients should be counseled to avoid activities requiring mental alertness until they know how these agents affect them.