Papaverine Hydrochloride 10% Maruishi
Papaverine Hydrochloride 10% Maruishi Uses, Dosage, Side Effects, Food Interaction and all others data.
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Papaverine Hydrochloride 10% Maruishi is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Papaverine Hydrochloride 10% Maruishi are exerted on cardiac and smooth muscle. Like qathidine, Papaverine Hydrochloride 10% Maruishi acts directly on the heart muscle to depress conduction and prolong the refractory period. Papaverine Hydrochloride 10% Maruishi relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Papaverine Hydrochloride 10% Maruishi and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Papaverine Hydrochloride 10% Maruishi is practically devoid of effects on the central nervous system. Papaverine Hydrochloride 10% Maruishi relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.
| Trade Name | Papaverine Hydrochloride 10% Maruishi |
| Availability | Prescription only |
| Generic | Papaverine |
| Papaverine Other Names | Papaverina, Papaverine |
| Type | |
| Formula | C20H21NO4 |
| Weight | Average: 339.385 Monoisotopic: 339.147058165 |
| Protein binding | ~90% |
| Groups | Approved, Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | Japan |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Papaverine Hydrochloride 10% Maruishi is an alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
For the treatment of impotence and vasospasms.
Papaverine Hydrochloride 10% Maruishi is also used to associated treatment for these conditions: Vascular spasm, Visceral spasms
How Papaverine Hydrochloride 10% Maruishi works
Perhaps by its direct vasodilating action on cerebral blood vessels, Papaverine Hydrochloride 10% Maruishi increases cerebral blood flow and decreases cerebral vascular resistance in normal subjects; oxygen consumption is unaltered. These effects may explain the benefit reported from the drug in cerebral vascular encephalopathy.
Food Interaction
No interactions found.Papaverine Hydrochloride 10% Maruishi Drug Interaction
Major: ciprofloxacinModerate: arginine, sildenafilMinor: tadalafilUnknown: aspirin, epinephrine, contained in alcoholic beverages , aspirin, ubiquinone, rosuvastatin, fluticasone nasal, metoprolol, gabapentin, acetaminophen, thiamine, cyanocobalamin, pyridoxine, ascorbic acid, cholecalciferol, phytonadione
Papaverine Hydrochloride 10% Maruishi Disease Interaction
Half Life
0.5-2 hours
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