Perboric acid
Perboric acid Uses, Dosage, Side Effects, Food Interaction and all others data.
Perboric acid is mainly found in its salt form of sodium perborate and it can be found as a monohydrate or tetrahydrate. It is one of the peroxy acid salts with very wide functionalities in industrial settings. Perboric acid in the form of sodium perborate is approved by Health Canada since 2004 to be used as a disinfectant of medical instruments. By the FDA, sodium perborate is approved as an ointment for the protection of poison ivy dermatitis.
No systemic effects are expected as it is highly unlikely that the substance will be systemically available.
| Trade Name | Perboric acid |
| Generic | Perboric acid |
| Type | |
| Formula | BHO3 |
| Weight | Average: 59.82 Monoisotopic: 60.001874 |
| Protein binding | As perboric acid and its sodium salt are rapidly degraded in the body, this pharmacokinetic property is studied in the terms of Sodium carbonate and Hydrogen peroxide. |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
In the industry, sodium perborate is used as a disinfectant. It is also part of the ingredients for detergents, bleach powders, and personal care formulations. In cosmetic products, perboric acid and mainly its salt are used as an oxidizing agent for dyeing or permanent waving.
In dentistry, sodium perborate monohydrate is used as an aid for the removal of phlegm, mucus or other secretions associated with an occasional sore in the mouth, for cleansing minor wounds, for temporary cleanse of canker sore or for the removal of foreign materials in minor wounds.
In ophthalmic preparations, sodium perborate is used as a preservative for products used for dry eye. This use is approved as this compound rapidly degrades to harmless byproducts.
Perboric acid is also used to associated treatment for these conditions: Canker sores oral, Minor gum inflammation, Ulceration of the mouth, Wound site
How Perboric acid works
Perboric acid acts as a source of active oxygen. In contact with water, perboric acid hydrolyzes to hydrogen and borate. As an antiseptic, the formation of hydrogen peroxide oxidizes the cellular components of the surrounding bacteria and kills them.
Toxicity
Acute oral and dermal LD50 are 1500 mg/kg and >2000 mg/kg, respectively. The toxicity of perboric acid and its salt is thought to be local and reported to be slight irritation of the skin which can be explained by the release of hydrogen peroxide. Mutagenicity, fertility and carcinogenicity studies have not been performed but it is thought that the potential of perboric acid to produce mutagenic, fertility or carcinogenic effects is unlikely.
Food Interaction
No interactions found.Volume of Distribution
As perboric acid and its sodium salt are rapidly degraded in the body, this pharmacokinetic property is studied in the terms of Sodium carbonate and Hydrogen peroxide.
Elimination Route
Dermal absorption is assumed to be very low due to the high hydrophilicity of perboric acid and its ionic nature.
Half Life
As perboric acid and its sodium salt are rapidly degraded in the body, this pharmacokinetic property is studied in the terms of Sodium carbonate and Hydrogen peroxide.
Clearance
As perboric acid and its sodium salt are rapidly degraded in the body, this pharmacokinetic property is studied in the terms of Sodium carbonate and Hydrogen peroxide.[
Elimination Route
As perboric acid and its sodium salt are rapidly degraded in the body, this pharmacokinetic property is studied in the terms of Sodium carbonate and Hydrogen peroxide.
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