Phenazon
Phenazon Uses, Dosage, Side Effects, Food Interaction and all others data.
An analgesic and antipyretic that has been given by mouth and as ear drops. Phenazon is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Phenazon is an analgesic and antipyretic that has been given by mouth and as ear drops. Phenazon is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
| Trade Name | Phenazon |
| Generic | Antipyrine |
| Antipyrine Other Names | Analgesine, Antipyrine, Fenazon, Fenazona, Phenazon, Phenazone |
| Type | |
| Formula | C11H12N2O |
| Weight | Average: 188.2258 Monoisotopic: 188.094963016 |
| Groups | Approved, Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Phenazon is an antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
Phenazon is an analgesic often used to test effects of other drugs on liver enzymes.
In combination with benzocaine in otic solutions, antipyrine is indicated for the symptomatic relief of acute otitis media arising from various etiologies.
Phenazon is also used to associated treatment for these conditions: Cough, Otitis Media (OM), Buccopharyngeal anesthesia
How Phenazon works
Phenazon is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis.
Food Interaction
- Take with or without food. When taken after meals, the Cmax and Tmax of oral antipyrine are reduced, but the overall bioavailability is not significantly impacted.
Innovators Monograph
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