Phenylalanine

Phenylalanine Uses, Dosage, Side Effects, Food Interaction and all others data.

Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.

Used by the brain to produce Norepinephrine, a chemical that transmits signals between nerve cells and the brain; keeps you awake and alert; reduces hunger pains; functions as an antidepressant and helps improve memory.

Trade Name Phenylalanine
Generic Phenylalanine
Phenylalanine Other Names Fenilalanina, L-Phenylalanine, Phenylalanine, Phenylalaninum
Type
Formula C9H11NO2
Weight Average: 165.1891
Monoisotopic: 165.078978601
Groups Approved, Investigational, Nutraceutical
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Phenylalanine
Phenylalanine

Uses

Phenylalanine is an amino acid commonly found as a component of total parenteral nutrition.

L-phenylalanine may be helpful in some with depression. It may also be useful in the treatment of vitiligo. There is some evidence that L-phenylalanine may exacerbate tardive dyskinesia in some schizophrenic patients and in some who have used neuroleptic drugs.

Phenylalanine is also used to associated treatment for these conditions: Amino acid supplementation

How Phenylalanine works

The supposed antidepressant effects of L-phenylalanine may be due to its role as a precursor in the synthesis of the neurotransmitters norepinephrine and dopamine. Elevated brain norepinephrine and dopamine levels are thought to be associated with antidepressant effects.
The mechanism of L-phenylalanine's possible antivitiligo activity is not well understood. It is thought that L-phenylalanine may stimulate the production of melanin in the affected skin

Toxicity

L-phenylalanine will exacerbate symptoms of phenylketonuria if used by phenylketonurics. L-phenylalanine was reported to exacerbate tardive dyskinesia when used by some with schizophrenia.

Elimination Route

Absorbed from the small intestine by a sodium dependent active transport process.

Innovators Monograph

You find simplified version here Phenylalanine

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