Plitidepsina Uses, Dosage, Side Effects and more
Aplidine is a peptide found in tunicates which shows promise in shrinking tumors in pancreatic, stomach, bladder, and prostate cancers. The specific marine organism is Aplidium albicans. Aplidine is also of interest as a potential treatment for some leukemias.
| Attribute | Details |
|---|---|
| Trade Name | Plitidepsina |
| Generic | Plitidepsin |
| Plitidepsin Other Names | Dehydrodidemnin B, Plitidepsin, Plitidepsina, Plitidepsine, Plitidepsium |
| Type | |
| Formula | C57H87N7O15 |
| Weight | Average: 1110.357 Monoisotopic: 1109.626015129 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Intended for the treatment of various forms of cancer.
How Plitidepsina works
Aplidine inhibits the growth and induces apoptosis in MOLT-4 cells through the indirect inhibition of VEGF secretion which blocks the VEGF/VEGFR-1 autocrine loop necessary for the growth of these cells.
